Rapid Mixer Granulator (RMG)

Rapid Mixer Granulator (RMG)

A RapidMixer Granulator (RMG) is a high-efficiency machine used primarily in the pharmaceutical, food, chemical, and cosmetic industries for wet granulation—a critical step in the tablet and capsule manufacturing process. It blends dry powders and granulates them rapidly by adding a liquid binder. RMGs ensure uniform mixing and granule formation, enhancing tablet compressibility and product quality.

Key Features of Rapid Mixer Granulator

1. High-speed Impeller and Chopper System – For rapid and uniform mixing.
2. Stainless Steel Construction (SS 316/SS 304) – Hygienic and corrosion-resistant.
3. Controlled Binder Addition – Via spray nozzles for consistent granule formation.
4. User-friendly Control Panel (PLC/HMI) – Easy operation and process monitoring.
5. Automated Discharge Valve – Ensures quick and clean granule transfer.
6. Variable Speed Settings – Impeller and chopper speeds can be adjusted.
7. Safety Interlocks and CIP/WIP Systems – For safe operation and easy cleaning.
8. Short Batch Time – Saves time and increases productivity.
9. GMP-Compliant Design – Meets global pharmaceutical manufacturing standards.
10. Scalable Sizes Available – Lab-scale to production-scale models.

Applications of Rapid Mixer Granulator

• Pharmaceutical Industry – For mixing and granulating excipients, APIs, binders.
• Nutraceuticals – Granule formation for herbal, protein, and vitamin supplements.
• Food Industry – Used in powdered food products and instant mixes.
• Chemical Industry – For uniform blending and granulation of powder chemicals.
• Cosmetic Industry – Used in compact powder and dry formulation preparation.

Uses of Rapid Mixer Granulator

• Wet Granulation – Binds powders using a liquid to form granules.
• Mixing Active and Inactive Ingredients – Ensures homogeneous blending.
• Improving Flow Properties of Powders – For smooth tablet compression.
• Pre-tableting Process – Ideal for preparing materials before compression.
• Reducing Dust and Enhancing Safety – By converting powders into granules.
• Granulation of Heat-sensitive Materials – Due to short processing time.

Benefits of Rapid Mixer Granulator

• Faster Processing Time – Granulation in minutes instead of hours.
• Uniform Granule Size – Enhances compressibility and tablet quality.
• Improved Bioavailability – Granules dissolve better than loose powders.
• Low Heat Generation – Protects sensitive ingredients.
• Efficient Binder Distribution – Minimizes batch rejection.
• Easy to Clean and Maintain – Supports WIP (Wash In Place) systems.
• Reduces Labor Cost – Automated systems reduce manual intervention.
• Safe Operation – With multiple safety interlocks and controls.
• Scalable – From R&D scale to large production batches.
• Consistent Output – Batch-to-batch quality is uniform and reproducible.

FAQs About Rapid Mixer Granulator (RMG)

1. Q: What is the main function of an RMG?
   A: To mix dry powders and form granules by adding a binder solution, mainly used in pharmaceutical tablet manufacturing.
2. Q: What industries use Rapid Mixer Granulators?
   A: Primarily pharmaceuticals, but also used in food, chemicals, and cosmetics.
3. Q: What is the difference between an impeller and a chopper in RMG?
   A: The impeller mixes the bulk powder, while the chopper breaks down lumps and ensures even granule formation.
4. Q: Can it be used for heat-sensitive materials?
   A: Yes, the short processing time minimizes heat generation, making it safe for thermolabile substances.
5. Q: What capacity options are available?
   A: RMGs range from lab-scale (1–10L) to industrial-scale (up to 1000L or more).
6. Q: Is the machine easy to clean?
   A: Yes, most RMGs come with WIP/CIP systems and smooth surfaces for easy cleaning.
7. Q: What materials are used in construction?
   A: Typically SS304 or SS316 for all contact parts to ensure GMP compliance.
8. Q: How is binder added in an RMG?
   A: Usually through a spray nozzle for uniform distribution during granulation.
9. Q: What are the safety features?
   A: Lid interlocks, emergency stop buttons, overload protection, and sensor-based systems.
10. Q: Can it be integrated into a full line?
    A: Yes, RMGs are often integrated with fluid bed dryers, multi-mill machines, and tablet presses for seamless production.

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Email - mkt@venusmachinery.com

Address : 29, Sarovar Industrial Estate, Hathijan Circle, S.P. Ring Road, Vatva, Ahmedabad - 382445, INDIA