Roller Compactor Machine for Pharmaceutical Industry

Roller Compactor Machine for Pharmaceutical Industry

A RollerCompactor Machine is a critical piece of equipment in modern pharmaceutical manufacturing, designed to densify powders into uniform granules through a dry granulation process. It operates by pressing powder between two counter-rotating rollers under high pressure, producing compacted sheets or ribbons that are then milled into granules. This method is ideal for moisture- and heat-sensitive materials, making it especially valuable for pharmaceutical applications.

Frequently Asked Questions (FAQs)

1. What is a roller compactor used for in pharmaceuticals?
   It’s used for dry granulation, turning fine powders into granules without using liquids or heat—ideal for moisture-sensitive drugs.
2. How does a roller compactor work?
   Powder is fed between two rollers under pressure to form a ribbon or compacted sheet, which is then milled into granules.
3. What are the key components of a roller compactor?
   The main components include feeding system, compression rollers, flake crusher, granulator, and control panel.
4. Is roller compaction a dry or wet granulation method?
   It is a dry granulation process, eliminating the need for binders or drying stages.
5. What types of materials can be processed?
   It can process API powders, excipients, herbal extracts, and other compressible powders.
6. Is the machine suitable for continuous processing?
   Yes, modern roller compactors support continuous production, enhancing batch consistency and throughput.
7. Are your machines cGMP and FDA compliant?
   Absolutely. Our machines are designed to meet cGMP, FDA, and 21 CFR Part 11 compliance standards.
8. What particle size is achievable with roller compaction?
   Particle sizes can be adjusted and typically range between 100 µm to 2 mm, depending on the application.
9. Can the machine be used in pilot-scale as well as production-scale?
   Yes, we offer lab-scale, pilot, and full production models for flexible manufacturing needs.
10. What safety and automation features are included?
    Our machines include overload protection, automatic pressure control, touch-screen PLC systems, and safety interlocks.

Applications in the Pharmaceutical Industry

• Granule preparation for tablet compression
• Dry granulation of moisture-sensitive drugs
• Controlled-release formulation development
• Processing of antibiotics, vitamins, and nutraceuticals
• Pre-compression of fine API powders for better flow
• Continuous production of solid oral dosage forms
• Granule formation for capsule filling
• Preparation of excipient blends
• Compression of herbal or plant-based powders
• OTC (over-the-counter) medicine manufacturing

Benefits of a Pharmaceutical Roller Compactor

• Eliminates need for binders and solvents
• Ideal for heat- and moisture-sensitive APIs
• Consistent granule size with excellent flowability
• Reduces dust and improves operator safety
• Low energy consumption and cost-effective
• Compact, hygienic, and easy-to-clean design
• Enables continuous production lines
• Fully automated controls ensure repeatability
• Minimizes product loss and increases yield
• Supports both small-batch and large-scale production

Common Uses of Roller Compactor Machines

• Producing compressible granules for tablets
• Improving the flow properties of bulk powders
• Eliminating segregation in multi-component blends
• Reducing particle size variability in production
• Dry compaction of botanical extracts in herbal medicine
• Creating uniform granules for capsule machines
• Pre-granulation before final tablet compression
• Converting hygroscopic or unstable powders into stable granules
• Manufacturing effervescent and chewable tablets
• Facilitating continuous manufacturing setups

Contact us more detail :

Call - +91 99746 08708

Email - mkt@venusmachinery.com

Address : 29, Sarovar Industrial Estate, Hathijan Circle, S.P. Ring Road, Vatva, Ahmedabad - 382445, INDIA